Effect of Implant Duration, Anatomical Location and Electrode Orientation on Bandwidth Recorded with a Chronically Implanted Endovascular Stent-Electrode Array

N Opie; S John; G Rind; S Ronayne; Clive May; David Grayden; Thomas Oxley

Conference Proceedings

Effect of Implant Duration, Anatomical Location and Electrode Orientation on Bandwidth Recorded with a Chronically Implanted Endovascular Stent-Electrode Array

N Opie, S John, G Rind, S Ronayne, Clive May, David Grayden, Thomas Oxley

2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) | IEEE | Published : 2018

DOI: 10.1109/EMBC.2018.8512385

Abstract

Access to the brain to implant recording electrodes has conventionally required a craniotomy. To mitigate risks of open brain surgery, we previously developed a stent-electrode array that can be delivered to the cortex via cerebral vessels. Following implantation of a stent-electrode array (Stentrode) in a large animal model, we investigated the longevity of high-quality signals, by measuring bandwidth in animals implanted for up to six months; no signal degradation was observed. We also investigated whether bandwidth was influenced by implant location with respect to the superior sagittal sinus and branching cortical veins; it was not. Finally, we assessed whether electrode orientation had ..

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University of Melbourne Researchers

Nicholas Opie Author

Sam John Author

Gil Rind Author

Stephen Ronayne Author

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Grants

Awarded by National Foundation for Medical Research and Innovation

Funding Acknowledgements

Research was supported by the National Foundation for Medical Research and Innovation, the Westpac Bicentennial Foundation and an Australian Research Council (ARC) Linkage Project (LP150100038).